- Healthcare professionals, government officials and everyday people find themselves in the midst of a pandemic as the CDC works to find a cure.
- Soon after her return from a business trip to Hong Kong, Beth Emhoff dies from what is a flu or some other type of infection. Her young son dies later the same day. Her husband Mitch however seems immune. Thus begins the spread of a deadly infection. For doctors and administrators at the U.S. Centers for Disease Control, several days pass before anyone realizes the extent or gravity of this new infection. They must first identify the type of virus in question and then find a means of combating it, a process that will likely take several months. As the contagion spreads to millions of people worldwide, societal order begins to break down as people panic.
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- Beth Emhoff (Gwenyth Paltrow) returns from a business trip to Hong Kong with a stop over at the Chicago airport, where she has sex with her former lover. Beth feels ill, but thinks the problem is jet leg. She travels back home to Minneapolis and spreads the virus to her son Clark and her husband, Mitch. When Beth and Clark die, Mitch goes in quarantine where the doctors realise he is immune to the mysterious virus. Meanwhile in Hong Kong, London and in a small province, cases of the mystery illness are cropping up, as the American CDC and the World Health Organization give their best effort researching the virus. A race against the clock begins, as the virus is spreading in a geometric progression, and if no solution is found - very fast - humanity will cease to be.
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Spoilers
Synopsis
- DAY 2
Beth Emhoff (Gwyneth Paltrow) is coughing in an airport lounge and gets a call from John Neal (voice of director Steven Soderbergh, in his uncredited cameo role), an old acquaintance who she just had sex with. A montage where we see several other people ensues.
A young man in Hong Kong gets off a boat, sweating. He goes home to his family and his sister looks at him concerned.
In London, a model gets sick and goes back to her hotel room. Hotel staff come into the room and find her dead on the bathroom floor.
On a plane, a businessman comes out of the lavatory with a pained expression on his face. He is traveling back home to Tokyo. He is on a bus when he collapses to the floor, convulsing. His death is captured on a camera phone.
The young man from Hong Kong leaves his apartment, coughing near several people in an elevator. He walks the streets, his vision getting more hazy. He walks into traffic and is hit by a truck and killed.
Finally, in Minnesota, Beth comes home to her husband Mitch (Matt Damon) and son Clark (Griffin Kane), hugging them both.
DAY 3
Dr. Ellis Cheever (Laurence Fishburne) comes into work at the Atlanta-based Center for Disease Control and Prevention (CDC). On the way in, he passes a janitor named Roger (John Hawkes) who he is on friendly terms with due to the football pool they have. Roger asks Cheever about his son since the school thinks he has ADHD. Roger asks if Cheever could look at him but Cheever says he is not that kind of doctor. However, he knows some people so he will try to refer a good doctor to Roger for his son.
Meanwhile, Mitch goes to pick up from Clark from school from what they think is a fever. Mitch tells Clark he will beat it by Thanksgiving.
At a news office a blogger journalist and conspiracy theorist, named Alan (Jude Law), is talking to an editor, named Lorraine, about the Tokyo bus incident. Alan thinks it may have to do with mercury poisoning in fish worldwide. Lorraine says they don't have the budget for this kind of freelance work but Allen says this story can go worldwide in 24 hours. Lorraine says she will pass it to another editor. Allen tells her he recorded this conversation and if she steals his story he will sue her.
DAY 4
Beth is at home, getting worse. She stares at a cup of coffee and tries to pick it up as Mitch talks about his day. She instead makes it fall off the counter and shatter. Mitch comes to help clean it up, when Beth starts to have a seizure. Mitch is scared, and he sees Clark at the doorway looking at his mother convulsing. Mitch tells him to go upstairs as he calls 911.
At the hospital, Mitch tries to explain what happened and Beth's allergies when she has another seizure and Mitch is pushed out of the room. A doctor comes to see him later and tells him Beth has just died. Mitch is in shock and asks to talk to her, not computing the news. The doctor tries to explain that his wife might have picked something up in China but there are no health alerts there to match to any of her symptoms. The medical board is going to order an autopsy in order to determine what killed her. Mitch is aghast and screams, "What happened?!"
Mitch is being driven home when he gets a call. His son is sick. He tells the babysitter to call 911. When he gets home, the babysitter says Clark had a headache so she put him to bed. By the time Mitch gets there, it is too late, his son is dead.
DAY 5
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In Switzerland, Dr. Leonora Orantes (Marion Cotillard), goes to work at the World Health Organization (WHO). She handles a briefing on this unknown virus and the cases of infection in the U.S., China, London and Japan. She expresses the need for the WHO to be thorough in its investigations. She mentions Beth as being the potential start of the infection.
Back in Hong Kong, the sister of the young man that was infected has his body cremated and goes to take his ashes away for burial via bus. A cleaning lady is checking the bus when she finds the girl dead. Her brother clearly infected her too before he died.
In Chicago, Beth's lover John Neal is being carried out on a stretcher. He has been infected as well. His wife looks on in shock, wondering what is wrong.
Two medical morticians do the autopsy on Beth, opening up her skull. They notice something strange about her brain. One of the men asks if he should take a sample. "Actually, I want you stand away from the table!" The other technician tells him. The technician tells his partner to call EVERYONE.
DAY 6
Dr. Erin Mears (Kate Winslet) is being briefed by Ellis on her job on the mysterious virus outbreak. She is to investigate and contain cases of infection. If she needs anything she can call him, no questions asked. Erin travels to Minnesota to be transported to a nearby CDC office.
Mitch is taken back to the hospital and put under quarantine watch. His teenage daughter from his previous marriage, Jory Emhoff (Anna Jacoby-Heron), arrives. They talk on a phone. Jory feels guilty of not being there when Clark died, but Mitch says it is not her fault. In addition, if she had been, she could have been infected too. She is all he has left. Mitch tells Jory to go home to her mother, but Jory says she will not leave him. She is staying with him.
Erin gives a briefing about the virus and the precautions they need to take. One woman asks if they are panicking about something they know little of. "We don't even know what to tell people to be afraid of." Mears notes that the virus is a contagion of touch. So the littlest things people touch and interact with, including each other, are potential harbors for infection. The problem, Mears says, is the carriers and the number they will potentially infect, the R-naught number. Flu is usually one person. Polio, pre-vaccine, was between four and six. Until they know more, this virus' R-naught number could be much greater.
Two doctors, Ally Hextall (Jennifer Ehle) and David Eisenberg (Demetri Martin) go into a secure bio lab and look at the samples taken from Beth's body among others. Hextall says they need to send it to Dr. Ian Sussman (Elliott Gould). Ian is another doctor in a less secure bio medical facility then theirs. He is leaving when he is accosted by Allen about accusations that this virus is being manufactured as a potential profiting scheme by drug companies. Sussman tells him to make an appointment and insults Allen's journalism saying, "Blogging is graffiti with punctuation."
DAY 7
Cheever is met at the CDC doors by Homeland Security agents. He is briefed by their liaison, Lyle Haggerty (Bryan Cranston). Homeland Security believes the virus might be a terrorist action as it is the only way terrorists have not tried to kill people. Cheever is intrigued by the theory but unconvinced. Haggerty mentions that someone could try to weaponise the Avian flu but Cheever counters that by saying, "They don't need to. The birds are doing it for us."
A news report states that the school Clark attended is being closed after three nurses and two other children die. A panic starts to form.
Mears goes to the AIMM offices where Beth worked. Many interacted with Beth before she left the country for China, so their fears are assuaged by Mears. Mears notes none had direct contact with Beth after she came home. One remembers Eric Barnes, another co-worker, drove her home from the airport. Mears calls him as he is on a bus. She tells him to get off as he is infected. He waits at the stop until Mears arrives with a containment crew.
Meanwhile, Mitch is being asked by a doctor about Beth. Mitch knows little of substance. The doctor asks about her Chicago layover, and if Beth knew anyone there. Mitch mentions that his wife was with John Neal before they married. Realisation hits Mitch. He asks if Neal is infected. The doctor is resistant but eventually nods. Mitch is stunned that his wife was cheating on him with her former boyfriend.
Hextall and Eisenberg give a briefing to Cheever about the virus sample taken from Beth's body. It latches onto the host cell, taking over completely. The body doesn't know what to do and the virus continues to attack. They noticed there are traces of bat and pig in the virus DNA code so it mostly originated from an infected bat. Understanding the severity of the issue, Cheever orders Sussman to be shut down and their secure lab is the only place where research will be done. Hextall calls Sussman and reluctantly tells him to shut down and destroy his samples.
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